Pre-embryos

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Epithelial cadherin distribution in abnormal human pre-implantation embryos.

BACKGROUND E(epithelial)-cadherin is a vital cell adhesion protein that plays a critical role in morphogenesis. Previous studies of E-cadherin distribution in human embryos have produced equivocal results. METHODS Immunocytochemistry in conjunction with laser scanning confocal microscopy was used to detect E-cadherin in 97 human cleavage stage embryos and 35 blastocysts from normal and abnorm...

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Expression of csal1 in pre limb-bud chick embryos.

The spalt family of transcriptional repressors has been implicated in limb, heart, ear and kidney development and truncating mutations in a human gene, SALL1, result in the autosomal dominant disorder Townes-Brocks syndrome. Here we show the expression pattern of the chick orthologue of the SALL1 gene, csal1, during early development. We found csal1 expression in the heart and in the pharynx, a...

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Frozen Pre-embryos and the Right to Change One’s Mind

Biological technology used for purposes of human reproduction has generated a number of issues involving contract law, genetic parenthood, and public policy. One such issue arises from disagreements about the fate of frozen embryos. This issue presents special challenges to the judicial process even though historically courts have had experience in applying reason to the most emotional of issue...

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Melatonin upregulates ErbB1 and ErbB4, two primary implantation receptors, in pre-implantation mouse embryos

Objective(s): To evaluated the effects of melatonin on early embryo competence and the expression rate of the primary implantation receptors (ErbB1 and ErbB4). Materials and Methods: Two-cell mouse embryos were cultured in 3 groups: simple media, melatonin-treated (10-9 M melatonin) and Luzindole-treated (10-9 M luzindole). Then, the rate of ErbB1 and ErbB4 gene and protein expression, the leve...

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Expression of arylamine N-acetyltransferases in pre-term placentas and in human pre-implantation embryos.

Arylamine N -acetyltransferases (NATs) catalyse the acetylation from acetyl-CoA of arylamines and hydrazines. There are two human isoenzymes which show polymorphism, and both enzymes are involved in the activation and detoxification of environmental carcinogens and teratogens. The two human isoenzymes NAT1 and NAT2 show different tissue distribution, with human NAT2 being found in liver and int...

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ژورنال

عنوان ژورنال: Nature

سال: 1986

ISSN: 0028-0836

DOI: 10.1038/321376b0